منابع مشابه
The Relative Bioavailability of Ibuprofen After Administration With a Novel Soft Chewable Drug Formulation
The first aim of the present study was to evaluate the bioavailability of ibuprofen dispersed in a novel soft chewable formulation compared with a traditional ibuprofen tablet; its second was to map the quality of taste masking and patient product satisfaction. In a phase 1, single-center, open-label, randomized, crossover study, healthy subjects received a soft-chew formulation or a hard table...
متن کاملNovel chewable colon targeted tablets of bumadizone calcium for treatment of ulcerative colitis: Formulation and optimization
The aim of the present study was the formulation of a novel chewable tablet containing the non-steroidal anti-inflammatory bumadizone calcium (BZ) to deliver the drug to the colon for the local treatment of ulcerative colitis. Colon targeted granules were prepared following 32 full factorial design. The effect of two independent variables, namely, polymer type (Eudragit ® S100, Eudragit ® L100,...
متن کاملFormulation and evaluation of chewable modified-release tablet containing sodium fluoride and vitamin C
Chewable modified release tablets containing two active ingredients vitamin C (200mg) and Sodium Fluoride (2mg) were formulated for the treatment of dental diseases. Other ingredients include Mannitol, Carbopol and Hydroxyl-Propyl Methylcellulose (HPMC), in different ratios. These tablets were prepared by direct mixing of Hydroxypropyl Methylcellulose (HPMC), vitamin C, Sodium Fluoride, Carbopo...
متن کاملDistances on Lozenge Tilings
In this paper, a structural property of the set of lozenge tilings of a 2n-gon is highlighted. We introduce a simple combinatorial value called Hamming-distance, which is a lower bound for the flipdistance (i.e. the number of necessary local transformations involving three lozenges) between two given tilings. It is here proven that, for n ≤ 4, the flip-distance between two tilings is equal to t...
متن کاملRandomized Placebo‐Controlled Clinical Trial of a Chewable Formulation of Amlodipine for the Treatment of Hypertension in Client‐Owned Cats
BACKGROUND There is an unmet clinical need for a cat-specific formulation of amlodipine to treat hypertensive cats. OBJECTIVES To assess the efficacy of chewable amlodipine tablets in reducing systolic blood pressure (SBP) in cats diagnosed with systemic arterial hypertension. ANIMALS Seventy-seven client-owned cats with systemic hypertension were included (median age 14 years). METHODS T...
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ژورنال
عنوان ژورنال: International Research Journal of Pharmacy
سال: 2016
ISSN: 2230-8407
DOI: 10.7897/2230-8407.07432